Current Research Projects

MERIT

d-MannosE to prevent Recurrent urine InfecTions

We are looking for women aged 18 years or over, who have had two or more urine infections (UTIs / cystitis) in the last six months, or three in the last 12 months, to take part in this study.

The study involves taking either a type of sugar (d-Mannose, a naturally occurring sugar found in fruit such as cranberries, apples, and oranges), or a placebo (harmless dummy), to see if it is effective at preventing further infections, and if it helps to avoid having to use antibiotic.

If you are interested in taking part in the study, please complete this form or contact the surgery for an information pack.

PriMUS

Primary care Management of lower Urinary tract Symptoms in men

We are looking for adult men who have troublesome urinary symptoms. These symptoms may include needing to pee frequently, difficulty passing urine, getting up at night to use the toilet, or poor flow.

The aims of the PriMUS study is to create a ‘decision aid’ to help GPs find the most likely cause of patients’ urinary symptoms, so that together they can choose the best treatment. We believe that this will have many benefits such as getting the right treatment sooner, avoiding unnecessary hospital visits, and getting those who need to be seen by a specialist there more quickly.

You can read more about the study on the PRiMUS website and if you’d like to take part please let the surgery know.

DECIDE

A Pragmatic Trial to Evaluate the Comparative Effectiveness Between Dapagliflozin and Standard of Care in Type 2 Diabetes Patients

This study is looking for patients with Type 2 Diabetes, who currently take metformin but whose blood glucose (sugar / HbA1c) is too high and need to start an extra medication. It hopes to look at the effectiveness of a medication called Dapagliflozin compared to other anti-diabetic medications.

Patients who choose to take part are randomly allocated to either take the medication called ‘Dapagliflozin’ or any other diabetic medication.

If you would like to take part, please discuss this during your routine diabetic review appointment.

COPD PASS

Post-authorisation Safety (PAS) Observational Cohort Study to Quantify the Incidence and Comparative Safety of Selected Cardiovascular and Cerebrovascular Events in COPD Patients Using Inhaled UMEC/VI Combination or Inhaled UMEC versus Tiotropium (Study 201038)

Patients who have COPD, and are starting one of three different types of inhaler are being asked to take part in this study which is comparing safety of different types of inhaled medications

Other Studies

We have other research studies currently still in progress but are now closed to recruiting new patients. These include:

  • BARACK-D: Benefits of aldosterone receptor antagonism in chronic kidney disease
  • HEAT: Helicobacter eradication to prevent ulcer bleeding in aspirin users trial
  • METNA RA: evaluating a new tool to help assess patient adherence to their arthritis medication
  • GENTHYR: Genetics of hypothyroidism study, looking into role of T3 and T4 combination therapies in specific subsets of hypothyroidism